Manufacturers of heat-stable LPV/r formulations and all relevant stakeholders involved commit to:

Jointly agree upon and execute next steps to optimize the availability and delivery of these formulations in 2019 including:

• Timely and regular information sharing (including orders placed and timelines for deliveries)

• Providing best possible demand forecasts

• Collaborate on the optimization of limited supply within and among countries and joint prioritization among orders to ensure sustainable supplies to children once initiated

• Support product uptake at country level

• Regulatory filings as needed to support scale-up, timely responses to queries raised during the review, and implementation (re-validation as required) of post approval changes at risk during the review period.