Donors commit to: 

 

105. Work towards reducing disease funding silos for diagnostics in order to encourage and support more comprehensive diagnostic strategies, including person-centred care, diagnostic integration and network optimization. 

 

106. Support improved global and national coordination across donors, including funding mechanisms, pooling procurement volumes in negotiations with diagnostic manufacturers, and other activities.

 

107. Prioritize and re-invigorate paediatric-specific funding for strengthened implementation of HIV and TB diagnostics and support of person-centred diagnostic technologies (ie. point-of-care infant diagnosis, simplified TB sample types). 

 

108. Support current efforts to transition from outright instrument procurement to all-inclusive bundles, or other novel pricing model to ensure in-country harmonization of commodity procurement.

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109. Support in a transparent manner, including key performance indicators, the procurement of commodities and operational costs to maintain and further scale-up POC infant diagnosis, as well as viral load testing for infants, children, and pregnant and breastfeeding women and advanced HIV disease diagnostics, including TB, as an integral part of optimized and integrated national diagnostic networks and in accordance with national plans and targets.

 

110. Continue (and expand) support to WHO PQ to broaden their mandate as planned and to shorten timelines for review and minimize time to national registration. 

 

PEPFAR commits to:

 

116. Work towards reducing disease funding silos for diagnostics in order to encourage and support diagnostic integration and multiplex testing to allow use of current platforms to address multiple diseases.

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117. Accelerate multi-disease diagnostic network optimization at the national level to support increased access to testing and network efficiencies, decrease total cost per test, and improvement in specimen-to-clinical action turnaround.

 

118. Continue engaging governments for policy change in support of all-inclusive pricing models and accelerated complementary use of point-of-care and centralized platforms.

 

119. Ensure implementing agencies and partners are aware of current paediatric diagnostics that can be procured with PEPFAR funds and ensure safe and ethical HIV testing services are offered to all biological children of parents living with HIV and biological siblings of children living with HIV This can include further scaling appropriate/approved use of HIVST assays including caregiver assisted oral self-testing for screening children at home. 

 

120. Expanding case finding modalities to find undiagnosed children and conducting audits of children newly testing positive for HIV––to inform new approaches to find the missing children, including improving demand generation linked to clinical services through multiple avenues.

 

121. Working with partners to improve CLHIV estimates through innovative data collection methods in tandem with household surveys.

 

122. Work with African based institutions to strengthen their capacity for regional regulatory approval of products.

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All partners commit to: 

 

163. Address inequities by tackling the stigma and discrimination in communities, schools, and healthcare settings that prevent children living with HIV from accessing testing and treatment. 

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164. Increase literacy about CD4 testing and viral load and promote a client-centred approach to support expansion of access to viral load for pregnant and breastfeeding women and children on treatment, including at the point-of-care. 

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165. Review and assess emerging co-infections for immunocompromised infants and children, including those with advanced HIV disease, such as severe bacterial infections, fungal infections, and others for country consideration and implementation.

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166. Engage affected communities for input and guidance on investment and programmatic priorities, provide support to in-country civil society organizations to engage in advocacy and demand creation for new tools, and ensure data is publicly available to support communities and civil society to monitor progress regarding uptake and implementation of essential diagnostic tools.

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